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Ketamine can produce rapid improvements in depression symptoms within hours, but the medication alone doesn’t create lasting change. Ketamine-assisted psychotherapy combines the neurobiological effects of ketamine with structured therapeutic work, translating temporary shifts in brain chemistry into durable improvements in how you think, feel, and live.
Nomad Therapeutics provides complete ketamine-assisted psychotherapy throughout Seattle, Tacoma, and South Seattle. This isn’t ketamine treatment with therapy added as an afterthought. It’s an integrated program where medication sessions and psychotherapy work together from the beginning, designed specifically to produce meaningful, sustained improvements rather than temporary symptom relief.
Ketamine-assisted psychotherapy follows a structured three-phase approach that repeats throughout your treatment. Each phase serves a specific purpose in helping you move from where you are now to where you want to be.
The preparation phase happens before each medication session. You’ll work with your therapist to set intentions for the upcoming ketamine experience, identify what you want to focus on, and prepare yourself mentally and emotionally for the session ahead. This isn’t just logistical planning. Preparation shapes what happens during the ketamine experience and influences what insights or perspectives emerge.
The medication phase is when a registered nurse administers ketamine via intramuscular injection in your home or your therapist’s office. During this session, the ketamine creates a temporary state where your usual patterns of thinking and feeling become more flexible. You might access emotions you’ve kept buried, see your life from a different angle, or experience a sense of distance from problems that normally feel overwhelming. Throughout this experience, your nurse provides full medical monitoring while you engage with whatever arises.
The integration phase follows each medication session. This is where the real work of therapy happens. You’ll meet with your therapist to process what you experienced, identify insights that emerged, and most importantly, translate those insights into concrete changes in your daily life. Integration transforms a temporary altered state into lasting behavioral shifts.
This three-phase cycle repeats across our standard protocol of six ketamine sessions over three weeks, creating multiple opportunities to prepare, experience, process, and integrate.






Ketamine creates a temporary window where your brain becomes more receptive to change. Research shows that ketamine enhances the brain’s natural ability to form new connections and adapt existing patterns. During this window, rigid ways of thinking and emotional responses that have kept you stuck become temporarily more flexible.
This window alone doesn’t create lasting change. The neurobiological shifts ketamine produces typically fade within days to weeks. What makes ketamine-assisted psychotherapy effective is using this window of heightened neuroplasticity to do therapeutic work that otherwise might take much longer or feel impossible to access.
When you’re in this more flexible state, you can step back from entrenched patterns of thinking that fuel depression or anxiety. You might access buried emotions you’ve avoided for years. You can see your life, your relationships, and your challenges from perspectives that weren’t available to you before. Most importantly, you can begin forming new neural pathways that support healthier ways of thinking and being.
The structured psychotherapy ensures these temporary shifts translate into lasting changes. Your therapist helps you understand what you experienced, identify what matters most, and create specific plans for bringing new insights into your daily life. Without this integration work, the ketamine experience remains just an experience. With skilled therapeutic support, it becomes a catalyst for sustained improvement in mood, behavior, and quality of life.
Ketamine-assisted psychotherapy requires coordination between medication sessions and therapy sessions. Nomad Therapeutics offers two pathways for this therapeutic partnership.
If you already work with a therapist who has training in ketamine-assisted psychotherapy, you can continue that existing relationship. We’ll coordinate the timing of medication sessions with your therapy schedule, ensuring your therapist can provide preparation before each session and integration afterward. This continuity allows you to build on therapeutic work you’ve already done while adding the powerful tool of ketamine-assisted treatment.
If you don’t currently have a therapist or your therapist doesn’t have ketamine-assisted psychotherapy training, we can connect you with a KAP-specialized therapist through the Nomad Network. These therapists understand the unique aspects of working with ketamine experiences and know how to help you translate what happens during medication sessions into meaningful life changes.
Either way, Nomad Therapeutics handles the medication administration while your therapist guides the preparation and integration work. This collaborative model ensures you receive expert care at every phase of treatment, with clear coordination between all providers involved in your healing.
The difference between ketamine treatment and ketamine-assisted psychotherapy is the difference between temporary symptom relief and lasting behavioral change. Medication alone can reduce depression symptoms rapidly, but without therapeutic integration, those improvements often fade when the ketamine’s acute effects wear off.
Research demonstrates that the therapeutic context surrounding ketamine administration significantly influences treatment outcomes. Patients who receive ketamine as part of structured psychotherapy show more sustained improvements than those who receive medication sessions alone. The preparation helps you approach the experience with intention rather than passivity. The integration therapy helps you hold onto insights and translate them into action rather than letting them slip away as the altered state fades.
Ketamine-assisted psychotherapy addresses root causes rather than just symptoms. The medication creates an opportunity for change, and the therapy provides the structure and support needed to actually make those changes stick. Together, they produce improvements in quality of life that persist well beyond the treatment protocol itself.
This complete approach reflects Nomad Therapeutics’ commitment to treatments that create durable results. We’re not interested in providing temporary relief that requires continuous medication to maintain. Our goal is helping you develop new ways of thinking, feeling, and living that remain effective long after your treatment sessions conclude.
Nomad Therapeutics follows a standard protocol of six ketamine sessions over three weeks. This timeframe provides enough repetition for the prepare-experience-integrate cycle to create meaningful change while maintaining treatment intensity that prevents long gaps between sessions.
Before your first medication session, you’ll complete a clinical evaluation where a Nomad Therapeutics clinician reviews your medical history, discusses your treatment goals, and confirms that ketamine-assisted psychotherapy is appropriate for your situation. You’ll also begin preparation sessions with your therapist.
Each medication session happens at a location you choose: your home or your therapist’s office in the Seattle, Tacoma, or South Seattle area. A registered nurse arrives with all necessary equipment, administers the ketamine via intramuscular injection, and provides full medical monitoring throughout the experience. After each medication session, you’ll schedule integration therapy to process what emerged and identify how to bring insights into your daily life.
Throughout the three-week protocol, you’re working on root causes of treatment-resistant depression, anxiety, or PTSD rather than just managing symptoms. The combination of ketamine’s neurobiological effects and skilled psychotherapy creates space for the kind of deep change that traditional approaches often struggle to reach.
Whether you’re in Tacoma, South Seattle, or anywhere in the greater Seattle area, Nomad Therapeutics brings this complete ketamine-assisted psychotherapy program to you.

Orientation &
Dose Finding
(Sessions 1-2)

The Neuroplastic
Window
(Sessions 3-4)

Consolidation
& Transition
(Sessions 5-6)
No commitment — just a conversation about which intervention might be right for you. A Nomad Therapeutics representative will answer your questions and walk you through what to expect.